Rico Lewis started again for Manchester City vs Wolves, but was replaced at half-time for Nathan Ake in a defensive reshuffle.
Lewis, 18, was picked at right-back ahead of Kyle Walker and Joao Cancelo. Aymeric Laporte started at left-back with Manuel Akanji and John Stones at central defence.
At half-time, Guardiola shuffled his pack and brought on Ake for Lewis, sending the Dutchman to left-back, moving Laporte inside alongside John Stones, and switching Manuel Akanji to right-back.
Explaining the switch, Guardiola said: “No, no, no [Lewis injury]. I wanted to change to more solidity.
“I thought Adama could play again, I thought Nathan could control him better than anyone else. And Rico has to know that playing every two or three days at that age is not easy.”
Guardiola added: “He (Lewis) has to use his body to adapt himself. He was marking him a lot because Hwang Hee-chan was close to him. It was just to put more physical presence in that position.
“In the second-half, we conceded [chances] a little bit more because they pushed us a lot and made high pressing, they didn’t sit back, they showed courage. I know Julen [Lopetegui] really well, and I know he is going to do a fantastic job (at Wolves).”